Ok y’all, my Endometrial Receptivity results are in.
So this means the standard 5 days of progesterone pre-transfer is WRONG for this uterus, and I’m part of the 1 in 4 women whose IVF transfers were happening on the wrong day, and I’ll need to do another mock cycle, adding an extra day of progesterone before doing the biopsy, to see if that will put me into the Receptive zone.
But here’s my confusion – and a question I’m waiting to hear back from Igenomix (AKA Ivigen) on, because my doctor, not surprisingly, has no real opinion on. Any of you gals who’ve done ERA, I’d especially love your thoughts:
Here’s the deal:
- My ERA biopsy was done after five days/five shots of PIO, which is the standard protocol. As we did my daily PIO shots at 8pm, this means on biopsy day I had no PIO shot.
- HOWEVER… during all of my five cycles of DEIVF, the embryo transfers were all done after five days/SIX shots of PIO. Why? We were doing my daily PIO shots at 6am, so on transfer day I had an injection. For three out of five of the transfers, the progesterone was in my system for 6 or more hours.
So what the hell does this mean?
I wish I had a fucking clue.
You see, I’m the first patient my RE has done this with, so while he intellectually understands my question, he doesn’t know enough about ERA to recommend anything other than the standard Igenomix recommendation of re-doing it an extra 24 hours later. But my question is, if I’m pre-receptive at day 5, and my history is having failed implantation 4 out of 5 transfers at day 5 but with 6 doses of PIO in me, am I wasting my time doing it at 6 days/6 doses and should I jump to 7 days/7 doses?
I know, it made me dizzy just writing that last sentence.
So I emailed Igenomix, in hopes that they’ll connect me to their genetic counselor and not simply give me a rubberstamped answer or tell me to listen to my doctor, which means…?
Who the hell knows, but it does mean that I am back on estrogen, HA! Ahh, the irony after my recent “free at last” post about getting off of it. The sooner I can get this mock cycle over and done with, the better. So the next biopsy should be in mid-February if I canculated that right. I just have to figure out how many PIO days I’m gonna do.
Fuck a doodle doo, I dearly love playing doctor (NOT).
Ultimately, I’m sure I’ll just go forward with doing it at P+6, and stop being so damn impatient, as this is the very last one and I want to get this right (plus if I do it at P+7, I’ll still need to do one at P+6 just to make sure that’s receptivity date fo’ sho’. But I do get 5 minutes to whine…
Well, at least before this happened I had a great visit with my therapist. I hadn’t had a 1:1 with her in a while and it really really was a good thing. With my back all fucked up even more (I re-tweaked it a bit, pushing my progress back a few weeks, as I gauge my recent gains by my ability to put on my own shoes and socks with ease, which I now need help with again. Sonofabitch.), I literally was talking to her lying on her sofa. Yep, a Freud joke did slip out as I did that, heh.
But seriously, it was so good to have this talk with her, and really dig deep in talking about some of the things I’ve broached on this blog – my anxieties, my resentments, my fears towards taking more steps if the final embryo transfer should fail, and my overall acute sense of mortality that’s come up during this process.
If any of you are having these crazytown moments like I have, get thee into a kickass counselor like mine. The more I talked about it with her, the more two things became crystal clear:
- We want a family and if IVF doesn’t work this 6th and final try with the last of the good quality embryos, we’re going headfirst into domestic adoption. When I look back on my life in 50 years, I don’t want to say I didn’t make an effort.
- After what happened with my mother abandoning me during my miscarriage this summer, I came to an epiphany while I spoke to my therapist. And it’s a big one y’all, something we all tell ourselves intellectually but don’t always believe emotionally:
I am not my mother. I will never be like my mother. I am no longer afraid of turning out like her! I am going to be a GREAT mother!